According to Myerburg and Costellanos, the introduction of cardiac revascularization to medicine (coronary artery bypass grafting [CABG]) almost 50 years ago led to a decline in the age-adjusted mortality from coronary artery disease (CAD),1 but brought no change to the fraction of coronary deaths that are sudden and unexpected.1 Of the 650,000 who die annually in the US of CAD, 300,000├óÔé¼ÔÇ£350,000 succumb to sudden cardiac death (SCD),1,2 and another 57,000 to end-stage systolic congestive heart failure (CHF).3 This prognostic picture has not changed since the era before the introduction of revascularization by CABG operations in the late 1960s. With the new technology described here, the responsibility for timely diagnosis of asymptomatic CAD can be transferred from costly medical institutions to primary care physicians (PCPs) in the community. This alternative strategy of cost-effective early diagnosis will facilitate at long last the completion of the revolution of revascularization that began half a century ago.
Methods
The Technology
Three consecutive models of the current technology were developed, the first being the Non-Invasive Cardiac System (NICaS). This was an impedance cardiographic (ICG) monitor for non-invasive measurement of the cardiac output (CO) and its derivatives.4
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