In the second video from the Transcatheter Mitral Valve Implantation (TMVI) Round Table Discussion, the assembled panel of internationally-recognised opinion leaders discuss the role of Mitral Valve Modification in the treatment of Mitral Regurgitation.
Designed to support the continuous education of practicing physicians, this session shares leading opinion and addresses the following discussion points:
- Overview of available technologies
- Patient selection and assessment
- Summary of procedures, success rates and complications
- Short and medium term outcomes
- What’s in the pipeline?
The panel for this session comprises:
- Simon Kennon (Chair), London Chest Hospital, London, UK
- Georg Lutter, Christian-Albrechts-University of Kiel, Germany
- Neil E Moat, Royal Brompton & Harefield NHS Trust, Harefield, UK
- Darren Mylotte, Galway University Hospitals, Galway, Ireland
- Lars Søndergaard, Rigshospitalet Copenhagen University Hospital, Denmark
- Nina Wunderlich, Cardiovascular Center Darmstadt, Germany
Radcliffe Cardiology and Interventional Cardiology Review extend their thanks to all panel members.
Members of the panel have also provided the following references to aid viewers understanding of the discussion:
- 2'38: Siminiak T, Wu JC, Haude M, et al. Treatment of functional mitral regurgitation by percutaneous annuloplasty: results of the TITAN Trial. European Journal of Heart Failure, 2014: 931–938
- 2'38: Schofer J, Siminiak T, Haude M, et al. Percutaneous mitral annuloplasty for functional mitral regurgitation: results of the CARILLON Mitral Annuloplasty Device European Union Study. Circulation.2009; 120: 326-333
- 2'56: Seeberger J, Rinaldi M, SL Nielsen, et al. Off-pump transapical implantation of artificial neo-chordae to correct mitral regurgitation: the TACT Trial (Transapical Artificial Chordae Tendinae) proof of concept. J Am Coll Cardiol. 2014;63(9):914-919.
- 5'10: Mauri L, Foster E, Glower DD, et al. 4-year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation. J Am Coll Cardiol. 2013 Jul 23;62(4):317-28.
- 5'15: Franzen O, van der Heyden J, Baldus S, et al. MitraClip® therapy in patients with end-stage systolic heart failure. Eur J Heart Fail. 2011 May;13(5):569-76.
- 5'57: Auricchio A, Schillinger W, Meyer S, et al. Correction of mitral regurgitation in nonresponders to cardiac resynchronization therapy by MitraClip improves symptoms and promotes reverse remodelling. J Am Coll Cardiol. 2011 Nov 15;58(21):2183-9
- 8'35: Schurer RA, Douglas YL, van der Werf HW, et.al. Use of the MitraClip in high-risk patients with severe heart failure: are we ready to identify the right candidate? Eur J Heart Fail. 2013 Jul;15(7):715-6.
- 8'42: A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation (RESHAPE-HF)
- 8'43: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) Trial
- 11'00: Siminiak T, Dankowski R, Baszko A, et al. Percutaneous direct mitral annuloplasty using the Mitralign Bident system: description of the method and a case report. Kardiol Pol. 2013;71(12):1287-92
- 13'30: De Bonis M, Lapenna E, Lorusso R, et al. Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation. J Thorac Cardiovasc Surg. 2012 Nov;144(5):1019-24. Erratum in: J Thorac Cardiovasc Surg. 2013 Feb;145(2):617.
- 13'30: Timek TA, Nielsen SL, Lai DT, et al. Edge-to-edge mitral valve repair without ring annuloplasty for acute ischemic mitral regurgitation. Circulation. 2003 Sep 9;108 Suppl 1:II122-7
- 13'41: Borger MA, Kaeding AF, Seeburger J, et al. Minimally invasive mitral valve repair in Barlow's disease: Early and long-term results. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1379-85
Other Useful Resources include:
Carillion: www.cardiacdimensions.com/PhysicianResources/technology.html
Mitraclip: www.youtube.com/watch?v=GDxXTZ1I12s
Mitralign: www.mitralign.com/themitralignsystem
Neochord: www.youtube.com/watch?v=IVFPsA0wxuo